Mygale SARL was established on 31 January 1989 when 24-year-old Bertrand Decoster, a graduate of the École supérieure des techniques aéronautiques et de construction automobile, set out to build the first French Formula Ford car. The market was then dominated by Van Diemen, Reynard Motorsports, and Swift Cooper, making it difficult for a new entrant to establish a foothold. Mygale operated its own racing school at the Autodrome de Linas-Montlhéry near Paris to generate income and develop driver relationships.
Early momentum came through a series of podium finishes in French Formula Ford before victories accumulated in the mid-1990s. Patrice Gay took the French and European Formula Ford championships in 1995, and David Terrien won the French title in 1996. Jenson Button's 1998 Formula Ford Festival win in a Mygale gave the manufacturer international profile. The British Formula Ford championship fell to Mygale drivers repeatedly, and after the category switched to the Ford EcoBoost engine, Mygale served as sole chassis supplier during the 2012 British Formula Ford season. By that point the company had won nine consecutive British Formula Ford championships.
Mygale entered the Formula Renault market in 1995, immediately winning the French Formula Renault Championship and the Formula Renault Eurocup through Cyrille Sauvage. Further success followed in 1998 when Matthew Davies and Julien Beltoise finished first and second in the French championship and took the top two positions in the Eurocup standings as well. The company competed in open Formula Renault formulae until the series shifted to single-supplier arrangements that favoured Tatuus and Martini.
Mygale became a contracted chassis supplier for Formula BMW, functioning as a manufacturing contractor with BMW's subsidiary responsible for the design elements. The company also supplied chassis for Formula Renault Campus and other single-marque series.
As Formula Four emerged as the FIA's primary global junior single-seater category in the mid-2010s, Mygale produced F4 chassis used in the British Formula 4 Championship and the German ADAC Formula 4 Championship. These cars competed in series that used a standardised 1.6-litre turbocharged engine producing around 160 horsepower in an aerodynamically restricted package designed to provide close racing and a stepping stone between kart racing and Formula Three.
Mygale entered the Formula Three market in 2006 with its M-06 chassis. The M-07 successor appeared in limited numbers in British, German, and European Formula Three championships. A close partnership with Ultimate Motorsport in the British Formula Three Championship in 2007 yielded fifth place in the teams' standings. Formula Three remained a smaller component of Mygale's business compared to its dominant position in Formula Ford.
Mygale built a significant presence in Australia through Formula Ford, with Australian championship wins in 1999, 2000, 2007, 2008, 2009, 2011, 2012, and 2013. The company entered the North American market through the USF2000 series in 1999, working with DSTP Motorsports, and established a distributor partnership with Bryan Herta Autosport for the SCCA Formula F class in 2012. Jonathan Urlin's third-place finish in the 2002 USF2000 championship represented the company's best American result.
Over more than three decades Mygale became a consistent presence in the lowest rungs of formula car racing, producing chassis that launched the careers of Jenson Button, Danica Patrick, Anthony Davidson, and many other drivers who progressed to the top levels of motorsport. The company's strength lay in high-quality, affordable production rather than cutting-edge design innovation. In 2024 Ligier Automotive acquired a majority stake, formally integrating Mygale's manufacturing capabilities into the broader Ligier group the following year.