Page was born in Evansville, Indiana, and grew up moving frequently as an army family, attending twelve different schools before graduating high school in Highland Park, Illinois. He studied at the University of Tulsa and served six years in the U.S. Army. His surname was changed in childhood from Henstridge to Page following his mother's remarriage. He first attended the Indianapolis 500 in 1960.
Page's broadcasting career began at stations WAIV and WATI before he moved to WIBC in Indianapolis in 1968, where he was mentored by Sid Collins, the legendary Voice of the 500. On December 1, 1977, while conducting a helicopter traffic report, Page survived a serious crash when the helicopter went down near Speedway Senior High School in Speedway, Indiana. He suffered a compound ankle fracture but returned quickly to his duties.
From 1974 to 1976, Page served as a pit reporter for the Indianapolis Motor Speedway Radio Network. He became the IMSRN Chief Announcer in 1977, taking over from Sid Collins, who had died by suicide. Page held the radio Voice of the 500 role through 1987.
In 1978 he joined NBC, anchoring auto racing coverage — including IndyCar, NASCAR, Formula One, and NHRA — through 1987. He was also a commentator for the motorsports program American Sports Cavalcade on cable network TNN during the 1980s.
In late 1987, Page moved to ABC Sports as their lead anchor for CART Indy car racing including the Indianapolis 500. His three-man television booth of Page, Bobby Unser, and Sam Posey became a defining presence on ABC's Indy 500 telecasts through the 1990s. Page was the creator of the Delta Force intros, which debuted in 1988 — dramatic opening sequences using Alan Silvestri's score from the film The Delta Force, combined with a montage of race footage, that became known as the "Page Teases" and remained a popular fixture through 1998.
His work on the 1989 and 1990 Indianapolis 500 telecasts earned the Sports Emmy for Outstanding Live Sports Special. Page covered both CART and IRL events for ABC and ESPN from 1996 to 1998, then shifted briefly to CART-only before returning to full-time IRL coverage from 2002. In 2005 he was moved off IndyCar and reassigned to the X Games, NHRA, and other events — a change that proved unpopular with audiences.
Page returned to the IMS Radio Network in 2009 as a guest analyst and reprised that role in multiple subsequent years. In 2014 and 2015 he returned as Chief Announcer, replacing Mike King. He co-anchored the milestone 100th Indianapolis 500 broadcast in 2016 before handing over primary duties to his successor.
From 2006 to 2012, Page was the lead announcer for NHRA Mello Yello Drag Racing on ESPN and ESPN2. He also announced Snocross races at the Winter X Games in the early 2000s, play-by-play for the Nathan's Hot Dog Eating Contest on ESPN from 2005 to 2017, and bull riding for the PRCA's Xtreme Bulls tour on ESPN in 2006.
In video games and film, Page gave the opening introduction to the Papyrus titles IndyCar Racing (1993) and IndyCar Racing II (1995), was the commentator voice for Destruction Derby 2 (1996), narrated scenes in the 2001 film Driven, and voiced the announcer character in the 2013 film Turbo.
Page was inducted into the Indianapolis Motor Speedway Hall of Fame in recognition of his half-century association with the race. His 15 Emmy Awards — two specifically for Indianapolis 500 coverage — along with his creation of the Delta Force intros and his tenure as radio Voice of the 500 on three separate occasions mark him as the central broadcasting figure in the history of the Indianapolis 500 as a television event. His autobiography, Hello, I'm Paul Page: "It's Race Day in Indianapolis," was published in 2022.