Blaise Alexander was born on March 26, 1976, in Montoursville, Pennsylvania. He began his stock car career at the age of twelve in the World Karting Association and was the champion of the East Series in 1992. From that point, Alexander moved onto the Micro-Sprint racing series at tracks in different states including Pennsylvania, Ohio, and New York, posting a total of 48 wins in the series. In 1995, Alexander moved from Montoursville to Mooresville, North Carolina, to pursue a racing career.
In 1995, Alexander began racing in the ARCA Re/Max Series, driving in a few races. He committed to a full season in 1996, earning ARCA’s Rookie of the Year Award. During his rookie season, he secured a second-place finish at Lowe’s Motor Speedway.
Alexander continued to race in ARCA, achieving two more second-place finishes in 1997. His breakthrough came in 1999 with wins at Toledo Speedway and Pocono Raceway. Throughout his ARCA career, he led in eighteen races for a total of 490 laps. He earned four career pole awards, at Michigan, Watkins Glen, Toledo and Winchester. In July 2001, Alexander won his final race at Michigan International Speedway.
In 1997, while continuing to race in fifteen ARCA events, Alexander began competing in NASCAR in the Busch Series and the Craftsman Truck Series. He had limited success in the Truck Series and modest results in Busch. In 2000, Alexander signed with Team SABCO for the Busch Series season, achieving two top-ten finishes and finishing 25th in points before returning to the ARCA series in 2001.
On October 4, 2001, during the ARCA EasyCare 100 at Lowe’s Motor Speedway, Alexander was involved in a fatal crash. He was battling for the lead with Kerry Earnhardt when Earnhardt, attempting to avoid a lapped car, braked sharply. This caused Alexander’s car to make contact with Earnhardt’s, sending Alexander’s car head-on into the outside retaining wall and then back into Earnhardt’s car. Alexander was knocked unconscious and pronounced dead at the infield care center at 10:20 PM, at the age of 25. Earnhardt immediately attempted to check on Alexander after the wreck, but was prevented from doing so by race officials .
Alexander’s death, caused by a basilar skull fracture, was the sixth driver fatality in two years, following the deaths of Dale Earnhardt, Adam Petty, Kenny Irwin Jr., and Tony Roper. His death, along with these others, prompted increased focus on driver safety. As a direct result of Alexander’s crash, NASCAR announced that the use of head and neck restraint devices would be required to keep drivers safe from these types of injuries . While 41 out of 43 drivers in NASCAR's top series were already using such devices, Alexander's death accelerated their universal adoption. NASCAR also eventually installed SAFER barriers on all NASCAR oval tracks, with most tracks covered by these barriers as of 2015.
After his 1995 move to North Carolina, Alexander enjoyed a close friendship with fellow Busch rookie driver and eventual NASCAR superstar, Jimmie Johnson, as they competed against each other on the track, while supporting each other off it. Other close relations included Spencer, who served as his mentor, and IndyCar driver P. J. Jones. Johnson dedicated his first Cup win to Alexander during a televised interview in Victory Lane, sent condolences in a Victory Lane interview after the death of Alexander's mother, and supported various charity causes and events that Alexander initiated in his hometown area of Central Pennsylvania. Shortly after Alexander's death, one of Johnson's crewmen drew a flame pattern with Alexander's initials on his driver's front left bumper; the tribute was continued in the form of a decal on Johnson's Cup cars. There are quite a few Blaise Alexander automotive dealerships in Central Pennsylvania originally created from his family.